Environmental Influences on Child Health Outcomes: Patient Reported Outcomes Research Resource Center Core (ECHO PRO Core) (U24)


The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for the Environmental influences on Child Health Outcomes (ECHO) Patient Reported Outcomes Research Resource Center Core (ECHO PRO Core). Working collaboratively with the other members of the ECHO Consortium and the Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium (see below), the ECHO PRO Core will conduct research (including development and validation of new instruments) and provide research services and resources to all ECHO Cohort Sites and Centers. The ECHO PRO Core will provide psychometric and medical expertise in the development, selection and use of PROs, child patient reported outcomes (cPROs), and proxy PROs for the evaluation of health and disease in children and other subjects being studied by the ECHO Cohort Sites. This FOA is one of seven companion FOAs that will establish the elements of the ECHO Consortium. Clinical Sites will collect clinical data and specimens from well-characterized participants. A Data Analysis Center (DAC) will oversee data standardization, integration, and storage, and will implement data sharing and computational tools for the integrated analysis of clinical and laboratory data. Overall coordination will be provided by an ECHO Coordinating Center (CC). Awardees will comprise the ECHO Consortium and must work collaboratively to plan and execute a large study to discover and characterize the impact of the environment on child health and disease. The product will be a publically available data resource that will enhance and accelerate subsequent mechanistic research on childhood diseases and conditions affected by environmental influences.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Agency: Department of Health and Human Services
Office: National Institutes of Health
Type(s) of Assistance Offered
Cooperative Agreement
Number of Awards Available
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
What is the process for applying and being award this assistance?
Other Assistance Considerations
Formula and Matching Requirements
This program does not have cost sharing or matching requirements.
Who do I contact about this opportunity?
Headquarters Office
NIH OER Webmaster
Website Address
E-mail Address
Financial Information