Trans-NIH Research Support


This listing covers multiple offices in the NIH Office of the Director that offer assistance awards or supplements to assistance awards.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
National Institutes of Health, Department of Health and Human Services
Type(s) of Assistance Offered
B - Project Grants; M - Training
Program Accomplishments
Not applicable.
Public Law 109-482
Public Health Service Act, Title IV, Section 402A, Public Law 109-482, 42 US Code 282A
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Awards can be made to domestic, public or private, for-profit or nonprofit organization, university, college, hospital, laboratory, or other institution, including State and local units of government, and individuals. Some initiatives will accept applications from foreign organizations. Additional details on eligibility are specified in each Funding Opportunity Announcement.
Beneficiary Eligibility
Institutions as described above.
Applications must be submitted in compliance with instructions provided with each initiative.
What is the process for applying and being award this assistance?
Pre-Application Procedure
Preapplication coordination is not applicable.
Application Procedure
2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Prepare and submit applications according to instructions provided in the applicable Funding Opportunities announcement. Most awards made under this program are subject to 2 CFR 200, as implemented by 45 CFR 75 "Public Welfare, Uniform Administrative Requirements, Cost Principles and Audit Requirements for HHS Awards". The policies and procedures generally applicable to NIH grants are set forth in the NIH Grants Policy Statement (
Award Procedure
Applications are reviewed for scientific and technical merit by a scientific review group and for program relevance by a national advisory council/board.
Contact the headquarters or regional location, as appropriate for application deadlines
Approval/Disapproval Decision Time
Not applicable.
Not applicable.
Not applicable.
How are proposals selected?
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
How may assistance be used?
To support research and other projects that will accelerate fundamental biomedical discovery and translation of that knowledge into effective prevention strategies and new treatments.
What are the requirements after being awarded this opportunity?
Not applicable.
Most awards made under this program are subject to the audit requirements of OMB 2 CFR 200, as implemented by 45 CFR 75, Subpart F, and in the NIH Grants Policy Statement (
Grantees generally must retain financial and programmatic records, supporting documents, statistical records, and all other records that are required by the terms of a grant, or may reasonably be considered pertinent to a grant, for a period of 3 years from the date the annual FSR is submitted. For awards under SNAP (other than those to foreign organizations and Federal institutions), the 3-year retention period will be calculated from the date the FSR for the entire competitive segment is submitted. Those grantees must retain the records pertinent to the entire competitive segment for 3 years from the date the FSR is submitted to NIH. Foreign organizations and Federal institutions must retain records for 3 years from the date of submission of the annual FSR to NIH. See 45 CFR 75 and 92.42 for exceptions and qualifications to the 3-year retention requirement (e.g., if any litigation, claim, financial management review, or audit is started before the expiration of the 3-year period, the records must be retained until all litigation, claims, or audit findings involving the records have been resolved and final action taken). Those sections also specify the retention period for other types of grant-related records, including F&A cost proposals and property records. See 45 CFR 75 and 92.36 for record retention and access requirements for contracts under grants. In accordance with 4 Code of Federal Regulations, Part 75, the HHS Inspector General, the U.S. Comptroller General, or any of their duly authorized representatives have the right of timely and unrestricted access to any books, documents, papers, or other records of recipients that are pertinent to awards in order to make audits, examinations, excerpts, transcripts, and copies of such documents. This right also includes timely and reasonable access to a recipient's personnel for the purpose of interview and discussion related to such documents. The rights of access are not limited to the required retention period, but shall last as long as records are retained.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formula is not applicable to this assistance listing.

Matching requirements are not applicable to this assistance listing.

MOE requirements are not applicable to this assistance listing.
Length and Time Phasing of Assistance
Almost all awards are made for at least one year, with additional support (up to four more years) depending on the recommendation of the scientific review group, the national advisory council, successful annual performance, and availability of funds. drawn from established accounts
Who do I contact about this opportunity?
Regional or Local Office
None/Not specified.
Headquarters Office
Michael Morse
6001 Executive Boulevard, Suite 8180, MSC 9500
Rockville, MD 20852 USA
Phone: 301-402-7617
Financial Information
Account Identification
(Project Grants) FY 22$446,362,230.00; FY 23 est $500,000,000.00; FY 24 est $475,000,000.00; - (Cooperative Agreements) FY 22$777,639,712.00; FY 23 est $855,000,000.00; FY 24 est $816,000,000.00; -
Range and Average of Financial Assistance
$1,970 to $22,378,886 with the average being $699,030.
Regulations, Guidelines and Literature
Not applicable.
Examples of Funded Projects
Not applicable.


Federal Grants Resources