The National Institute of Nursing Research (NINR) supports clinical and basic research to develop the scientific foundation for clinical practice, prevent disease and disability, manage and eliminate symptoms, enhance palliative and end-of-life care, improve innovation, and train the next generation of scientists. In doing so, the Institute’s scientific focus bridges multiple disciplines; uniting the biological and behavioral sciences to foster and improve the health of individuals, families, and communities across diverse populations and the lifespan in a variety of clinical settings. NINR research seeks to advance the science of health by (a) enhancing health promotion and disease prevention in diverse groups through culturally-appropriate interventions designed to encourage health equity and eliminate health disparities; (b) engaging individuals as active participants in their own health and improving symptom management in those with acute and chronic illness; (c) improving quality of life for patients with advanced illness through evidence-based palliative and end-of-life care; (d) developing new technologies and innovative programs to improve health and reduce healthcare costs; and, (e) preparing the next generation of nurse scientists and clinicians to address current and future health challenges and contribute to an innovative, multidisciplinary, and diverse scientific workforce. NINR’s research programs incorporate the use of interdisciplinary approaches designed to promote scientific exploration and generate improved health outcomes and services. These approaches include: basic science-driven clinical intervention studies; interdisciplinary and translational research strategies; analyses of cost, outcomes, and quality of care; and studies to assess and enhance the effectiveness of the nursing workforce. NINR also continues to uphold its strong commitment to addressing the health needs of minority and underserved populations, promote health equity, and build a diverse scientific workforce. Investing in Advancing the Quality of Life: Symptom Management: NINR’s research program to improve quality of life focuses on reducing the burdens of chronic and acute illness across both the spectrum of human diseases and the lifespan. The Investing in Health Promotion and Disease Prevention program investigates the key biological, behavioral, and social factors that promote long-term health and healthy behaviors and prevent the development of disease across health conditions, settings, and the lifespan. Investing in Palliative and End-of-Life Care: Under the NINR Palliative and End-of-Life Care program, researchers are applying interdisciplinary biological, behavioral, and social science strategies to advance understanding of the needs of individuals and their caregivers, and develop palliative care interventions to manage the symptoms of advanced illness. Through the Investing in Innovation program, NINR promotes technological advancements that address a range of health care challenges and facilitate the delivery of real-time personalized information to individuals and families, health care providers, and communities. Investing in Nurse Scientists: To develop a strong cohort of nurse scientists and contribute to an innovative, multidisciplinary, and diverse scientific workforce, the Investing in Nurse Scientists program emphasizes research training and career development. Intramural Research Program: The Intramural Research Program supports cutting-edge clinical and genomic research to better understand the underlying mechanisms of a variety of symptoms, their effect on patients, and how patients respond to interventions.
General information about this opportunity
Last Known Status
Agency: Department of Health and Human Services
Office: National Institutes of Health
Type(s) of Assistance Offered
Fiscal Year 2014: 263 research grants, 57 NRSA Individual FTTPs, 131 NRSA Institutional FTTPs. Fiscal Year 2015: 266 research grants, 57 NRSA Individual FTTPs, 151 NRSA Institutional FTTPs. Fiscal Year 2016: 264 research grants, 57 NRSA Individual FTTPs, 151 NRSA Institutional FTTPs.
Public Health Service Act, Section 301, 464, 487, 42 U.S.C 285q; Public Health Service Act, Public Law 99-158; Public Health Service Act, Public Law 102-564.
Who is eligible to apply/benefit from this assistance?
Research Grants: Any corporation, public or private institution or agency, or other legal entity, either nonprofit or for-profit, may apply. NRSAs (Individual): An applicant must be a registered professional nurse with either a baccalaureate and/or a master's degree in nursing and must be a citizen of the United States or lawfully admitted for permanent residence. Those on temporary or student visas are not eligible. NRSAs (Institutional): An eligible institution must be capable of providing predoctoral and/or postdoctoral research training opportunities for nurses. SBIR grants: can be awarded only to domestic small businesses (entities that are independently owned and operated for profit; are not dominant in the field in which research is being proposed; and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the United States or its possessions. To be eligible for funding, a grant application must be reviewed for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees) which "partner" with a research institution in cooperative research and development. At least 40 percent of the project is to be performed by the small business concern and at least 30 percent by the research institution. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.
Individuals and public or private institutions.
Each applicant for research projects must present a research plan and furnish evidence that scientific competence, facilities, equipment, and supplies are appropriate to carry out the plan. NRSAs (Individual): The applicant's academic record, research experience, citizenship, licensure as a registered nurse, and institutional sponsorship should be documented in the application. NRSAs (Institutional): The applicant organization must show the objectives, methodology and resources for the research training program, the qualifications and experience of directing staff, the criteria to be used in selecting individuals for awards, and detailed budget justification for the amount of grant funds requested. Costs will be determined in accordance with 2 CFR, Part 220, Cost Principles for Educational Institutions. For-profit organizations' costs are determined in accordance with 48 CFR Subpart 31.2 of the Federal Acquisition Regulations. For other grantees, costs will be determined by HHS Regulations 45 CFR, Part 75. For SBIR and STTR grants, applicant organization (small business concern) must present in a research plan an idea that has potential for commercialization and furnish evidence that scientific competence, experimental methods, facilities, equipment, and funds requested are appropriate to carry out the plan. The SF 424 (Research and Research-Related) application forms and the SF 424 SBIR/STTR Application Guide are used to apply for both SBIR and STTR, Phase I and Phase II. Application is made electronically through Grants.gov (http://www.grants.gov). 2 CFR 200, Subpart E - Cost Principles applies to this program.
What is the process for applying and being award this assistance?
Preapplication coordination is not applicable. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372.
2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Research Grants: Applications must be prepared either electronically through Grants.gov (http://www.grants.gov) using the SF 424 (Research and Research-Related). The format is interactive. For assistance contact GrantsInfo, Telephone (301) 435- 0714, Email: GrantsInfo@nih.gov. NRSAs (Individual): Individuals must submit the application form, PHS Individual National Research Service Award (PHS 416-1, rev. 10/05), and include at least three letters of reference. If the applicant has been lawfully admitted to the United States for permanent residence, the appropriate item should be checked on the Face Page of the application. Applicants who have applied for and have not yet been granted admission as a permanent resident should check the Permanent resident block on the Face Page of the PHS 416-1 application, and also write in the word "pending." A notarized statement documenting legal admission for permanent residence must be submitted prior to the issuance of an award. SBIR and STTR: The SF 424 (Research and Research-Related) application forms and the SF 424 SBIR/STTR Application Guide are used to apply for both SBIR and STTR grants, Phase I and Phase II. Application must be made electronically through grants.gov (http://www.grants.gov). For further assistance contact GrantsInfo, Telephone: (301) 435-0714, E-mail: GrantsInfo@nih.gov.
Research Grants and National Research Service Awards (NRSAs) (Institutional): All accepted applications are reviewed for scientific merit by an appropriate initial review group and then by a national advisory council. (Individual NRSA applications are not reviewed by council.) All applications favorably recommended compete for available funds on the basis of scientific merit and mission/program relevance. All accepted SBIR/STTR applications are evaluated for scientific and technical merit by an appropriate scientific peer review panel and by a national advisory council. All applications receiving a priority score compete for available SBIR/STTR set-aside funds on the basis of scientific and technical merit and commercial potential of the proposed research, mission/program relevance, and program balance among the areas of research.
Contact the headquarters or regional office, as appropriate, for application deadlines.
Approval/Disapproval Decision Time
Research Grants: From 6 to 9 months. NRSAs: From 6 to 9 months. SBIR/STTR: About 7-1/2 months. AIDS Grants: About 6 months.
Research Grants: A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the NINR. NINR follows the NIH Appeals policy, NOT-OD-11-064: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-11-064.html. NINR works with application Program Director/Principal Investigators (PD/PI) within the NIH appeals policy.
Research Grants: Renewal applications are accepted. NRSAs: Awards may be made for 1 to 5 years. No individual may receive more than 5 years of aggregate NRSA support beyond the predoctoral level, and no individual may receive NRSA support for more than 3 years of support beyond the postdoctoral level. Institutional awards may be renewed.
How are proposals selected?
Reviewers provide an overall impact/priority score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed): (1) Significance: Does the project address an important problem or a critical barrier to progress in the field? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?(2) Investigators: Are the PD/PIs, collaborators, and other researchers well suited to the project? If Early Stage Investigators or New Investigators, or in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project? (3) Innovation: Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed?(4) Approach: Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the project? Are potential problems, alternative strategies, and benchmarks for success presented? If the project is in the early stages of development, will the strategy establish feasibility and will particularly risky aspects be managed? If the project involves human subjects and/or NIH-defined clinical research, are the plans to address 1) the protection of human subjects from research risks, and 2) the inclusion (or exclusion) of individuals on the basis of sex/gender, race, and ethnicity, as well as the inclusion (exclusion) of children, justified in terms of the scientific goals and research strategy proposed? (5) Environment: Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?In addition to the above criteria, the following items will continue to be considered in the determination of scientific merit and the impact/priority score. Protections for Human Subjects: For research that involves human subjects but does not involve one of the six categories of research that are exempt under 45 CFR Part 46, the committee will evaluate the justification for involvement of human subjects and the proposed protections from research risk relating to their participation according to the following five review criteria: 1) risk to subjects, 2) adequacy of protection against risks, 3) potential benefits to the subjects and others, 4) importance of the knowledge to be gained, and 5) data and safety monitoring for clinical trials. For research that involves human subjects and meets the criteria for one or more of the six categories of research that are exempt under 45 CFR Part 46, the committee will evaluate: 1) the justification for the exemption, 2) human subjects involvement and characteristics, and 3) sources of materials. Inclusion of Women, Minorities, and Children: When the proposed project involves human subjects and/or NIH-defined clinical research, the committee will evaluate the proposed plans for the inclusion (or exclusion) of individuals on the basis of sex/gender, race, and ethnicity, as well as the inclusion (or exclusion) of children to determine if it is justified in terms of the scientific goals and research strategy proposed. Vertebrate Animals: The committee will evaluate the involvement of live vertebrate animals as part of the scientific assessment according to the following five points: 1) proposed use of the animals, and species, strains, ages, sex, and numbers to be used; 2) justifications for the use of animals and for the appropriateness of the species and numbers proposed; 3) adequacy of veterinary care; 4) procedures for limiting discomfort, distress, pain and injury to that which is unavoidable in the conduct of scientifically sound research including the use of analgesic, anesthetic, and tranquilizing drugs and/or comfortable restraining devices; and 5) methods of euthanasia and reason for selection if not consistent with the AVMA Guidelines on Euthanasia. Biohazards: Reviewers will assess whether materials or procedures proposed are potentially hazardous to research personnel and/or the environment, and if needed, determine whether adequate protection is proposed. Resubmission: The committee will evaluate the application as now presented, taking into consideration the responses to comments from the previous scientific review group and changes made to the project. Renewal: The committee will consider the progress made in the last funding period. Revision: The committee will consider the appropriateness of the proposed expansion of the scope of the project. If the Revision application relates to a specific line of investigation presented in the original application that was not recommended for approval by the committee, then the committee will consider whether the responses to comments from the previous scientific review group are adequate and whether substantial changes are clearly evident. Applications compete for available funds with all other recommended applications. The following will be considered in making funding decisions: Scientific merit of the proposed project as determined by peer review; Availability of funds; Relevance of program priorities.
How may assistance be used?
Research Grants: Funds may be used for salaries, consultation, equipment, travel and other usual costs, subject to Federal regulations applicable to the grant. National Research Service Awards (NRSAs) (Individual): Individual awards are made to institutions on behalf of the individual for research training in specified areas related to the mission of NINR. NRSAs (Institutional): Grants may be made to institutions to enable them to accept individuals for research training. Each individual who receives a NRSA postdoctoral fellowship on an NRSA award must comply with all applicable service and payback provisions. SBIR Phase I grants: (of approximately 6-months' duration) are to establish the technical merit and feasibility of a proposed research effort that may lead to a commercial product or process. Only Phase I awardees are eligible to apply for Phase II support. STTR Phase I grants (normally of 1-year duration) are to determine the scientific, technical, and commercial merit and feasibility of the proposed cooperative effort that has potential for commercial application. Phase II funding is based on results of research initiated in Phase I and scientific and technical merit and commercial potential of Phase II application.
What are the requirements after being awarded this opportunity?
Final reports including the financial status report on all projects are required within 90 days after their conclusion. No cash reports are required. Progress reports where applicable are required annually for continuing projects. Financial status reports where applicable are required annually for continuing projects. Progress reports where applicable are required annually for continuing projects.
In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503.
Grantees generally must retain financial and programmatic records, supporting documents, statistical records, and all other records that are required by the terms of a grant, or may reasonably be considered pertinent to a grant, for a period of 3 years from the date the annual FSR is submitted. For awards under SNAP (other than those to foreign organizations and Federal institutions), the 3-year retention period will be calculated from the date the FSR for the entire competitive segment is submitted. Those grantees must retain the records pertinent to the entire competitive segment for 3 years from the date the FSR is submitted to NIH. Foreign organizations and Federal institutions must retain records for 3 years from the date of submission of the annual FSR to NIH. See 45 CFR Part 75.361 for exceptions and qualifications to the 3-year retention requirement (e.g., if any litigation, claim, financial management review, or audit is started before the expiration of the 3-year period, the records must be retained until all litigation, claims, or audit findings involving the records have been resolved and final action taken). Those sections also specify the retention period for other types of grant-related records, including F&A cost proposals and property records. See 45 CFR Part 75.361 and Part 75.364 for record retention and access requirements for contracts under grants.
In accordance with 45 CFR 75.364, the HHS Inspector General, the U.S. Comptroller General, or any of their duly authorized representatives have the right of timely and unrestricted access to any books, documents, papers, or other records of recipients that are pertinent to awards in order to make audits, examinations, excerpts, transcripts, and copies of such documents. This right also includes timely and reasonable access to a recipient’s personnel for the purpose of interview and discussion related to such documents. The rights of access are not limited to the required retention period, but shall last as long as records are retained.
Other Assistance Considerations
Formula and Matching Requirements
This program has no statutory formula.
This program has no matching requirements.
MOE requirements are not applicable to this program.
Length and Time Phasing of Assistance
Research Grants: Awards are usually made annually with no project periods to exceed 5 years in length. NRSAs: Institutional awards may be made for up to 5 years, and Individual awards may be made for up to 5 years at the predoctoral level, 3 years at postdoctoral level, and 2 years at senior level. SBIR: Normally, Phase I awards are for 6 months; normally, Phase II awards are for 2 years. STTR: Normally, Phase I awards are for 1 year; normally, Phase II awards are for 2 years. See the following for information on how assistance is awarded/released: Grant awards are made annually.
Who do I contact about this opportunity?
Regional or Local Office
Ann Knebel 31 Center Drive, Bethesda, Maryland 20892 Email: email@example.com
(Project Grants) FY 14 $103,537,417; FY 15 est $104,525,000; and FY 16 est $107,340,000 - Research Grants. (Training) FY 14 $8,856,883; FY 15 est $9,236,000; and FY 16 est $9,236,000 - National Research Service Awards (NRSA).
Range and Average of Financial Assistance
FY14 Research Grants: $42,991 to $1,961,397; average cost $398,240.
NRSA Individual Awards: $2,573 to $54,230 average cost of FTTP/Award $34,774.
Institutional NRSA Awards: $52,810 to $557,741; average cost of FTTP $286,514.
Regulations, Guidelines and Literature
Research Grants: Grants will be available under the authority of and administered in accordance with the NIH Grants Policy Statement and Federal regulations at 42 CFR 52 and 42 USC 241; Omnibus Solicitation of the Public Health Service for Small Business Innovation Research (SBIR) Grant and Cooperative Agreement Applications. Omnibus Solicitation of the National Institutes of Health for Small Business Technology Transfer (STTR) Grant Applications.
Examples of Funded Projects
Fiscal Year 2014: No Current Data Available Fiscal Year 2015: No Current Data Available Fiscal Year 2016: No Current Data Available