Research on Chemical and Biological Defense


To further the capability to prevent, detect, diagnose and treat the effects of chemical, radiological and biological warfare agents.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Department of The Army, Department of Defense
Type(s) of Assistance Offered
B - Project Grants
Program Accomplishments
Fiscal Year 2023 Health monitoring to improve diagnosis and treatment chronic pain in US service members, telehealth platform to deliver therapeutic care for US service members at high risk for post traumatic osteoarthritis, evaluation of a running sock designed to provide real time biofeedback to healthy US service members.
10 U.S.C. 4001
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Applicants must be a public or private educational institution, a nonprofit organizations operated for purposes in the public interest, or a commercial firm.
Beneficiary Eligibility
Beneficiaries are relatively independent investigators associated with an applicant organization.
Applicants must furnish evidence of legal authorization, financial and managerial capability as well as a certification of compliance with Federal, State, and local environmental laws, ordinances and regulations. Applicants must be registered in System for Award Management (SAM). Also, the applicant, proposed subrecipients, and principals must not appear on the SAM Exclusions website as currently debarred, suspended, or otherwise ineligible. 2 CFR 200, Subpart E - Cost Principles applies to this program.
What is the process for applying and being award this assistance?
Pre-Application Procedure
Preapplication coordination is not applicable.
Application Procedure
2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. Applicants should obtain a copy of the relevant BAA which describes the full research program areas of interest and includes necessary forms and instruction for preproposal/proposal submissions. The BAA is available for download, at no cost to the applicant, at,, (search under ACC-APG-NCD), and
Award Procedure
Award procedures are contained in the BAA and available for download at (search under ACC-APG-NCD),, and describes the award procedures and criteria as well as the areas of interest and necessary forms and instructions for proposal submissions.
Any relevant deadline(s) will be listed in the BAA or individual announcements.
Approval/Disapproval Decision Time
From 60 to 90 days. See the relevant BAA or individual announcement.
Not applicable.
Once a grant is awarded, any follow-on research proposal may be treated as a new request. Follow-on work should allow for review time noted above.
How are proposals selected?
As specified in the relevant BAA or individual announcement
How may assistance be used?
Recipients are required to conform to their accepted research protocol and are usually required to submit some form of performance report.
What are the requirements after being awarded this opportunity?
Performance Reports: Performance monitoring is required as described in the individual announcement.
In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503.
Record keeping requirements are in accordance with the terms and conditions of the award, which will include appropriate provisions related to recipient records that are required by the DoDGARs.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formula is not applicable to this assistance listing.

Matching requirements are not applicable to this assistance listing.

MOE requirements are not applicable to this assistance listing.
Length and Time Phasing of Assistance
The length of time for which support is requested should be consistent with the nature and complexity of the proposed research. The maximum period acceptable for a research proposal is 5 years. Funds are normally released on a quarterly basis.
Who do I contact about this opportunity?
Regional or Local Office
None/Not specified.
Headquarters Office
Richard W. Totten
110 Thomas Johnson Drive
Frederick, MD 21702 US
Phone: 3016192446

Scott Hoffman
110 Thomas Johnson Dr.
Frederick, MD 21702 USA
Phone: 301-619-8482
Website Address
Financial Information
Account Identification
(Project Grants) FY 22$1,000,000.00; FY 23 est $100,000.00; FY 24 est $1,000,000.00; FY 21$1,000,000.00; FY 20$1,000,000.00; FY 19$843,414.00; FY 18$1,000,000.00; FY 17$0.00; FY 14$8,467,000.00; FY 16$0.00; FY 15$4,602,000.00; -
Range and Average of Financial Assistance
$10,000 - $1,000,000
Regulations, Guidelines and Literature
Department of Defense Grant and Agreement Regulations (DoDGARS) (as updated through DoD's interim implementation of 2 CFR part 200 which can be found at 2 CFR part 1103) and individual program announcements
Examples of Funded Projects
Fiscal Year 2023 Research related to medical/biological prophylaxis; prevention, treatment, or supportive care regimens for adverse reactions to prophylaxis or pretreatments against bio-warfare agents; Development of improved methods for delivery of vaccines, including adjuvants, nucleic acid vaccines, methods for oral or nasal immunization with inactivated, live and subunit antigens; sustained release formulations; and methods for delivery of antigens for specific induction of mucosal immunity and development of methods to enhance appropriate immune responses to include co- delivery of cytokines; prophylactic/pretreatment and therapeutic pharmaceuticals are non-vaccine pharmacological or biological products used to prevent or treat patients exposed to either chemical warfare agents (CWA) or biological warfare agents (BWA); Prophylactic/pretreatment and therapeutic pharmaceuticals are non-vaccine pharmacological or biological products used to prevent or treat patients exposed to either chemical warfare agents (CWA) or biological warfare agents (BWA).


Federal Grants Resources