The intent of the research funded through the Peer Reviewed Alzheimerâ€™s Research Program (PRARP) Quality of Life Research Award (QUAL)is to reduce the burden on affected individuals and caregivers, especially in the military and Veteran communities. The research impact will benefit the military, Veteran, and civilian communities. The QUAL is open to Principal Investigators (PIs) at or above the level of Assistant Professor (or equivalent) from any field or discipline who seek to bring their expertise to address the PRARPâ€™s mission. However, as part of the application, the PI should demonstrate that the study team has experience in both TBI and AD research. Preliminary data, while not required, is encouraged. FY15 QUAL Overarching Challenges: This QUAL funding opportunity requires applications to address one or more of the following FY15 Overarching Challenges: Quality of Life: The need for technologies, assessments, interventions, or devices to benefit individuals living with the symptoms of TBI and AD. Caregiver Burden: The need for technologies, assessments, interventions, or devices with the goal of reducing burden for caregivers of individuals living with the symptoms of TBI and AD. FY15 QUAL Focus Areas: In addition to addressing one or more of the specified FY15 Overarching Challenges, applications should address at least one of the following FY15 Focus Areas in support of the FY15 Overarching Challenges. An application that proposes research outside of these FY15 Focus Areas is acceptable, as long as the applicant provides a strong rationale: Care Interventions and Quality of Life: Research intended to stabilize or improve the quality of life of those affected by TBI or AD. Examples of research in this Focus Area include: identification and management of co-morbidities and modifiable risk factors (e.g., sleep apnea, obesity); cognitive training interventions; studies of health and wellness and behavioral interventions. Caregiver Support: Research intended to reduce the burden of care on the caregiver for individuals affected by the symptoms of TBI or AD. Examples of research in this focus area include: Caregiver training, home-based support, behavioral interventions, and relationship interventions. The following is specifically discouraged under the FY15 PRARP: Pharmacologic Interventions: Clinical or Basic research requiring investigational or U.S. Food and Drug Administration (FDA)-approved drugs or medicines.