TaRGET I: Chromatin Structure, Genomics, and Transcriptional Responses to the Environment (R01)

 

In order to understand the mechanisms by which toxicants impact gene expression, it is necessary to better understand how exposure affects the proteins and processes upstream of DNA methylation and other epigenetic marks. The NIEHS has made a significant investment in research aimed at identifying epigenetic signatures of exposure, but the mechanistic studies aimed at identifying how these epigenetic marks are established are currently under-represented in our portfolio. The purpose of this FOA is to encourage research applications that will potentially move the field from descriptive and correlative studies to an enhanced mechanistic understanding of how environmental exposures affect the proteins and functional genomic elements involved in establishing and maintaining gene expression patterns and chromatin states.

General information about this opportunity
Last Known Status
Deleted 12/20/2012 (Archived.)
Program Number
RFA-ES-12-008
Federal Agency/Office
Agency: Department of Health and Human Services
Office: National Institutes of Health
Type(s) of Assistance Offered
Grant
Number of Awards Available
5
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
What is the process for applying and being award this assistance?
Deadlines
11/19/2012
Other Assistance Considerations
Formula and Matching Requirements
This program does not have cost sharing or matching requirements.
Who do I contact about this opportunity?
Headquarters Office
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
Website Address
http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-12-008.html
E-mail Address
FBOWebmaster@OD.NIH.GOV
Financial Information
Obligations
$3,000,000.00
Range and Average of Financial Assistance
Awards up to $400,000.00

 


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