Research, Prevention, and Education Programs on Lyme Disease in the United States


To develop, implement and evaluate practical and effective measures for the primary and secondary prevention of Lyme disease in the United States.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Centers For Disease Control and Prevention, Department of Health and Human Services
Type(s) of Assistance Offered
B - Project Grants
Program Accomplishments
Fiscal Year 2016 In FY2016, one new cooperative agreement will be funded for Integrated Tick Management studies. Funding Opportunity Announcement no. CK16-002: Spatially scalable integrated tick vector/rodent reservoir management to reduce human risk of exposure to Ixodes scapularis ticks infected with Lyme disease spirochetes - Impact of single versus multi-property implementation in relation to human landscape use patterns and tick encounter locations. In FY2016, one new cooperative agreement was awarded for Integrated Tick Management studies. Funding Opportunity Announcement no. CK16-002: Spatially scalable integrated tick vector/rodent reservoir management to reduce human risk of exposure to Ixodes scapularis ticks infected with Lyme disease spirochetes - Impact of single versus multi-property implementation in relation to human landscape use patterns and tick encounter locations.
Fiscal Year 2017 In FY2017, it is expected that one cooperative agreement begun in FY2016 will be continued non-competitively.
Fiscal Year 2018 In FY2019, it is expected that one cooperative agreement begun in FY2016 will be continued for the last non-competitive continuation year of the project period.
Public Health Service Act, Section 301, 42 U.S.C. 241(a)
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Public and nonprofit organizations able to provide services to geographical areas where Lyme disease is endemic or found to be newly emerging in the continental United States. Thus, universities, colleges, research institutions, State and local health departments, and private nonprofit organizations are eligible.
Beneficiary Eligibility
States, political subdivisions of states, and other public and nonprofit private entities and the general public who may be exposed to the threat of Lyme disease in certain geographical areas.
Nonprofit organizations are corporations or associations no part of whose net earnings may lawfully inure to the benefit of any private shareholder or individual. Proof of nonprofit status must be submitted by private nonprofit organizations with the application or, if previously filed with PHS, the applicant must state where and when the proof was submitted.
What is the process for applying and being award this assistance?
Pre-Application Procedure
Preapplication coordination is required. Environmental impact information is not required for this program. An environmental impact assessment is not required for this listing. This program is eligible for coverage under E.O. 12372, "Intergovernmental Review of Federal Programs." An applicant should consult the office or official designated as the single point of contact in his or her State for more information on the process the State requires to be followed in applying for assistance, if the State has selected the program for review. This program has no preapplication requirements.
Application Procedure
2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards applies to this program. To apply to a published funding opportunity, applications must be submitted electronically through ( using the SF-424 Research and Related (R&R) forms and the SF-424 (R&R) Application Guide. Detailed application instructions are included in the Notice of Funding Opportunity (NOFO) for federal assistance. Online information can be found at HHS/CDC's Office of Financial Resources, Funding, Grants internet page: This program is subject to the provisions of 45 CFR 92 for State and local governments and OMB Circular No. A-110 for nonprofit organizations.
Award Procedure
Upon receipt, applications will be evaluated for completeness and responsiveness by the HHS/CDC Office of Grant Services and agency extramural program office. HHS/CDC will not review incomplete and non-responsive applications. After review and approval, a notice of grant award (NoA) is prepared and processed, along with appropriate notification to the public. Initial award provides funds for first budget period (usually 12 months) and NoA indicates support recommended for the remainder of the period of performance, allocation of Federal funds by budget categories, and special conditions, if any.
Contact the headquarters or regional location, as appropriate for application deadlines
Approval/Disapproval Decision Time
Approximately 3 to 6 months.
Not applicable.
Cooperative agreement periods of performance are typically for 3 to 4 years. Subject to availability of funds, after initial awards, projects may be renewed non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.
How are proposals selected?
Applications for public health research grants and cooperative agreements are evaluated for scientific and technical merit through the HHS/CDC peer review system. Applications are evaluated by a chartered Special Emphasis Panel in accordance with the Federal Advisory Committee Act, and in accordance with CDC peer review policy and manual. Applications will be evaluated on the review criteria described in the Notice of Funding Opportunity (NOFO). In general, the review and selection process of complete and responsive applications to the NOFO consists of determination of the scientific merit by peer review, availability of funds, and relevance of program priorities and the priorities of DHHS. Refer to the NOFO for additional review criteria.
How may assistance be used?
Funding opportunities are made available to develop disease surveillance, conduct ecological and epidemiological studies, develop prevention and control activities, develop better diagnostic tests, and develop and disseminate educational materials and programs. Cooperative Agreements include funds for direct costs, i.e., personnel, travel, equipment, supplies, necessary to carry out an approved project as well as funds for the reimbursement of applicable indirect costs. Unallowable costs, such as reimbursement of pre-award costs, as well as those for which prior written approval is required, are indicated in the Health & Human Services (HHS) Grants Policy Statement (
What are the requirements after being awarded this opportunity?
Performance Reports: Final performance reports are required no more than 90 days after the end of the project period. All reports must be submitted to the Grants Management Specialist indicated in the NoA.
Not applicable.
Financial records, supporting documents, statistical records, and all other records pertinent to the project must be kept readily available for review by personnel authorized to examine PHS grant accounts. Records must be maintained for a minimum of 3 years after the end of a budget period. If questions still remain, such as those raised as a result of an audit, records must be retained until completion or resolution of any audit in process or pending resolution. Property records must be retained in accordance with PHS Grants Policy Statement requirements.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formula is not applicable to this assistance listing.

Matching requirements are not applicable to this assistance listing.

MOE requirements are not applicable to this assistance listing.
Length and Time Phasing of Assistance
Assistance is available for a 12-month budget period within periods of performance typically ranging from 3 to 4 years. After awards are issued, funds are released in accordance with the payment procedure established by the recipient institution with DHHS' payment management system (PMS). PMS will forward instructions to the recipient for obtaining payments.
Who do I contact about this opportunity?
Regional or Local Office
Bacterial Diseases Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Office of Infectious Diseases, Centers for Disease Control and Prevention, 3156 Rampart Road, Fort Collins, CO 80521. Branch Extramural Activities Contacts: Ms. Diane Hamm - Telephone: (970) 221-6414 and Dr. Paul Mead - Telephone: (970) 221-6474. Division Extramural Activities Contacts: Ms. Lisa Mackey - Telephone: (970) 221-6415 or Dr. Charles (Ben) Beard - Telephone: (970) 221- 6418.
Headquarters Office
Christine Morrison
1600 Clifton Road, E60
Atlanta, GA 30329-4018 US
Phone: 404-718-8845
Fax: 404-718-8640
Website Address
Financial Information
Account Identification
(Cooperative Agreements (Discretionary Grants)) FY 18$462,404.00; FY 19 est $339,906.00; FY 20 est $0.00; FY 17$522,087.00; FY 16$299,992.00; - These obligations exclude federal assistance provided to the States through the Epidemiology and Laboratory Capacity (ELC) and Emerging Infections Program (EIP) cooperative agreements (covered under CFDA 93.283), and their supporting large contract(s) provided by program discretionary funds.
Range and Average of Financial Assistance
$250,000 to $500,000; Average award depends on Notice of Funding Opportunity (NOFO).
Regulations, Guidelines and Literature
Information on DHHS Grants Policies and Regulations may be found at Pertinent information may be obtained by contacting the Headquarters Office.
Examples of Funded Projects
Not applicable.


Federal Grants Resources