Human Pancreas Procurement and Analysis Program (HPPAP) (UC4)


This Funding Opportunity Announcement (FOA) invites cooperative agreement applications to develop and operate a Human Pancreas Procurement and Analysis Program (HPPAP). This FOA will support the assembly of a team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, analysis and distribution of human pancreatic tissues; and analysis and integration of complex biological datasets, that will be tasked to: 1) collect and intensively characterize primary pancreatic tissues from patients with T1D, pre-T1D (i.e. positive for multiple islet autoantibodies) or rare forms of islet dysfunction, 2) distribute these specimens and their extensive linked data to the larger research community for expanded analysis, and 3) organize the data collected from the study of these tissues into an open-access resource database (PANC DB). HPPAP will become a component of the Human Islet Research Network (HIRN) created in 2014 to support innovative and collaborative translational research to understand how human beta cells are lost in T1D, and to find innovative strategies to protect and replace functional human beta cell mass.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Agency: Department of Health and Human Services
Office: National Institutes of Health
Type(s) of Assistance Offered
Cooperative Agreement
Number of Awards Available
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
What is the process for applying and being award this assistance?
Other Assistance Considerations
Formula and Matching Requirements
This program does not have cost sharing or matching requirements.
Who do I contact about this opportunity?
Headquarters Office
NIH OER Webmaster
Website Address
E-mail Address
Financial Information
Range and Average of Financial Assistance
Awards up to $2,300,000.00


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