Great Lakes Human Health Effects Research

 

To: (1) Build upon and amplify the results from past and on-going research in the Great Lakes basin; (2) develop information, databases and research methodology that will provide long-term benefit to human health effects research in the Great Lakes basin; (3) develop direction for future health effects research; (4) provide state local health officials: the concerned public and their medical health care professionals; (5) in concert with State and local health offices increase the public awareness regarding the potential health implications of the toxic pollution problem in the Great Lakes basin; and (6) coordinate as necessary with relevant Public Health Service (PHS) research programs and activities, including those of the Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), and the Indian Health Service (IHS), as well as the Environmental Environment Protection Agency (EPA) and State and local health departments, to ameliorate adverse public health impacts of persistent toxic substances in the Great Lakes basin.

General information about this opportunity
Last Known Status
Deleted 11/01/2009 (Archived.)
Program Number
93.208
Federal Agency/Office
AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Type(s) of Assistance Offered
Project Grants.
Program Accomplishments
In fiscal year 2001, funding was provided for 10 competing awards. It is anticipated that there will be 10 noncompeting continuation awards in fiscal years 2002 and 2003.
Authorization
Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980, as amended; Superfund Amendments and Reauthorization Act of 1986, Sections 104 (i)(5)(A) and (15), Public Law 99-499; 42 U.S.C. 9604 (i)(5)(A) and (15); Great Lakes Critical Programs Act of 1990, Section 106, Subsection 118(e); 33 U.S.C. 1268(e)(3).
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Eligible applicants are the official public health agencies or their bona fide agents or instrumentalities and political subdivisions thereof, which may include State universities, State colleges, State research institutions, State and local health departments, and federally-recognized Indian tribal governments located in the Great Lakes States. This includes Illinois, Indiana, Michigan, Minnesota, Ohio, Pennsylvania, New York and Wisconsin and is consistent with Section 106, Subsection 118(e) of the Great Lakes Critical Programs Act of 1990 (33 U.S.C. 1268(e)(3)).
Beneficiary Eligibility
Native Americans, Minority Groups, Sport Anglers, Urban Poor, Individuals and Families who consume contaminated Great Lakes Fish.
Credentials/Documentation
Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments.
What is the process for applying and being award this assistance?
Pre-Application Procedure
None. An environmental impact statement is not required for this program. This program is excluded from coverage under E. O. 12372.
Application Procedure
Applicants must use application Form 5161-1. Application packets are available from: Acquisition and Assistance Branch A, Procurement and Grants Office, Centers for Disease Control and Prevention, 2920 Brandywine Road, Room 3000, Atlanta, GA 30341. By formal agreement, the CDC Grants Management Branch will act on behalf of ATSDR on this matter.
Award Procedure
The Assistant Administrator, ATSDR, has final authority to approve funding of applications. When an application is approved for funding, the Grants Management Officer, CDC, acting as agent for ATSDR, will prepare a Notice of Grant Award.
Deadlines
Contact the Headquarters Office identified below for application deadlines.
Approval/Disapproval Decision Time
Approximately 60 to 90 days.
Appeals
None.
Renewals
Awards are made for project periods of 1 to 3 years with 12-month budget periods. Renewals awards cannot be made beyond the project period without competition.
How are proposals selected?
Applications will be reviewed and evaluated according to the following criteria: Proposed Program; Program Personnel; Applicant Capability; and Program Budget (Not Scored).
How may assistance be used?
To conduct research on the impact on human health of fish consumption in the Great Lakes region. This Program of Research will focus on populations which have been identified to have a higher risk of long-term adverse health effects from exposure to contaminants in Great Lakes fish, i.e., Native Americans, sport anglers, urban poor, the elderly, Asian Americans, racial/ethnic minority populations, fetuses, and nursing infants of mothers who consume contaminated Great Lakes fish. Priority areas of research for this program include: 1. Characterizing exposure and determining the profiles and levels of Great Lakes contaminants in biological tissues and fluids in high-risk populations; 2. Identifying sensitive and specific human health endpoints, i.e., reproductive/developmental, behavioral, endocrinologic, and immunologic effects and correlating them to exposure to Great Lakes contaminants; and 3. Determining the short- and long-term risk(s) of adverse health effects in children which result from parental exposure to Great Lakes contaminants. Proposed projects covering these priority areas should include strategies (risk communication) to inform susceptible populations about the potential human health impact of consuming contaminated fish from the Great Lakes. Based upon research findings, longer term priority areas may include, but are not limited to: 1. Investigating the feasibility of, or establishing, registries and/or surveillance cohorts in the Great Lakes region; and 2. Establishing a chemical mixtures database with emphasis on tissue and blood levels to identify new cohorts, conduct surveillance and health effects studies, and establish registries and/or surveillance cohorts.
What are the requirements after being awarded this opportunity?
Reporting
Annual progress and financial status reports are required no later than 90 days after the end of each budget period. Final financial status and performance reports are required 90 days after the end of the project period.
Auditing
In accordance with the provisions of OMB Circular No. A- 133 (Revised, June 24, 1997), "Audits of States, Local Governments, and Nonprofit Organizations," nonfederal entities that expend financial assistance of $300,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $300,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133. In addition, grants and cooperative agreements are subject to inspection and audits by HHS and other Federal officials.
Records
Detailed and accurate records of travel expenditures, personnel hours and all other costs will be retained for 10 years in accordance with EPA's "Superfund Financial Management and Recordkeeping Guidance for Federal Agencies." Such documents may be required to provide the basis of cost recovery actions or other litigation. Additionally, this documentation must be available for audit or verification upon the request of the Inspector General.
Other Assistance Considerations
Formula and Matching Requirements
This program has no statutory formula or matching requirements.
Length and Time Phasing of Assistance
The awards will be made for 12-month budget periods within a project period of 1 to 3 years. Continuation awards within the project period are made on the basis of satisfactory progress and availability of funds.
Who do I contact about this opportunity?
Regional or Local Office
Not applicable.
Headquarters Office
Program Contact: Dr. Heraline E. Hicks, Division of Toxicology, Agency for Toxic Substances and Disease Registry, 1600 Clifton Road, NE, Mail Stop E-29, Atlanta, Georgia 30333. Telephone: (404) 489-0717. Fax: 404-498-0094. E-mail address: HEH2@cdc.gov. Grants Management Contact: Mildred Garner, Acquisition and Assistance Branch A, Procurement and Grants Office, Centers for Disease Control and Prevention, 2920 Brandywine Road, Room 3000, Atlanta, GA 30341. Telephone: (770) 488-2745. Fax: (770) 488-2777.
Website Address
http://www.atsdr.cdc.gov
Financial Information
Account Identification
75-8252-0-1-551.
Obligations
(Grants) FY 02 $1,187,000; FY 03 est $3,000,000; and FY 04 est $3,000,000.
Range and Average of Financial Assistance
$72,000 to $175,000; $119,000.
Regulations, Guidelines and Literature
Regulations governing this program are set forth in 45 CFR 92 and 40 CFR 35, subpart O. Guidelines are available in the application kit. PHS Grants Policy Statement No. 94-50,000 (Revised) April 1, 1994.
Examples of Funded Projects
(1) The New York State Angler Cohort Study: Exposure Characterization and Reproductive and Developmental Effects; (2) Great Lakes Fish as a Source of Maternal and Fetal Exposure to Chlorinated Hydrocarbons; (3) An Assessment of a Human Population at Risk: The Impact of Consuming Contaminated Great Lakes Fish on Native American Communities; (4) Cognitive and Motor Effects of PCB Exposure in Older People from the Michigan Fish Eaters Cohort: Emphasis on the Role of Ortho-Substituted Congeners; (5) Contribution of Nursing to Behavioral Changes in Offspring of Mothers Who Consumed Lake Ontario Fish: Two Methodological Approaches; (6) Health Risks from Consumption of Great Lakes Fish; and (7) Assessing Effects of Human Reproductive Health of PCB Exposure via Consumption of Great Lakes Fish. Three grants were awarded to State Health Departments for the following projects: (1) PCB and DDE Exposure among Native American Men from Contaminated Great Lakes Fish and Wildlife; (2) Consortium for the Health Assessment of Great Lakes Sport Fish Consumption; and (3) Michigan Great Lakes Health Studies.

 



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