Global AIDS


The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) is the U.S. Government initiative to help save the lives of those suffering from HIV/AIDS around the world. This historic commitment is the largest by any nation to combat a single disease internationally, and PEPFAR investments also help alleviate suffering from other diseases across the global health spectrum. PEPFAR is the cornerstone and largest component of the U.S. President’s Global Health Initiative. With a special focus on improving the health of women, newborns and children, the Global Health Initiative’s goal is to save the greatest number of lives by increasing and building upon what works and, then, supporting countries as they work to improve the health of their own people.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Agency: Department of Health and Human Services
Office: Centers for Disease Control and Prevention
Type(s) of Assistance Offered
Program Accomplishments
Not Applicable.
Sections 307 and 317(k)(2), Public Health Service Act, 42 U.S.C. 242I and 247b(k)(2) as amended; United States Leadership Against HIV/AIDS, Tuberculosis and Malaria Act of 2003, Public Law 110-293, the Tom Lantos and Henry J. Hyde United States Global Leadership Against HIV/AIDS, Tuberculosis, and Malaria Reauthorization Act of 2008, 22 U.S.C 7601; PEPFAR Stewardship and Oversight Act of 2013 (P.L. 113-56).
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Competition is limited, or single eligibility by authorizing legislation.
Beneficiary Eligibility
This is only for non-research and research activities supported by CDC/ATSDR. For the definition of research, please see the CDC web site at the following Internet address:
Your narrative should address activities to be conducted over the entire project period, and must include the following items in the order listed: 1) Organizational Experience; 2) Goals and Objectives; 3) Plan of Action; 4) Management plan, staffing, and infrastructure; and 5) Budget. This program is excluded from coverage under 2 CFR 200, Subpart E - Cost Principles.
What is the process for applying and being award this assistance?
Pre-Application Procedure
Preapplication coordination is required. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372.
Application Procedure
This program is excluded from coverage under 2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards. Applications for funding opportunities should be submitted via the website If you do not have access to the Internet, or if you have difficulty accessing the forms on-line, you may contact the CDC Procurement and Grants Office Technical Information Management Section (PGO-TIM) staff at; Telephone: (770) 488-2700. Application forms can be mailed to you. Submit the original and two hard copies of your application by mail or express delivery service to: Technical Information Management, CDC Procurement and Grants Office, 2920 Brandywine Road, Atlanta, GA 30341. Applications may not be submitted electronically at this time.
Award Procedure
Successful applicants will receive a Notice of Grant Award (NGA) from the CDC Procurement and Grants Office. The NGA shall be the only binding, authorizing document between the recipient and CDC. The NGA will be signed by an authorized Grants Management Officer, and mailed to the recipient fiscal officer identified in the application.
Oct 01, 2014 Applications must be received in the CDC Procurement and Grants Office by 5:00 p.m. Eastern Time on the deadline date.
Approval/Disapproval Decision Time
From 90 to 120 days.
Not Applicable.
From 60 to 90 days. Renewals are made by competitive applications and Reviews.
How are proposals selected?
Applications will be reviewed for completeness by the Procurement and Grants Office (PGO) staff, and for responsiveness by the Center for Global Health (CGH). Incomplete applications and applications that are non-responsive to the eligibility criteria will not advance through the review process. Applicants will be notified that their application did not meet submission requirements. An objective review panel will evaluate complete and responsive applications.
How may assistance be used?
Reimbursement of pre-award costs is not allowed. No funds shall be used to distribute sterile needles or syringes for the hypodermic use of any illegal drug. Funds may be spent for reasonable program purposes, including personnel, travel, operating costs including supplies, fuel for transportation, utilities, staff training costs including registration fees and purchase and rental of training related equipment, renovation of clinical or lab facilities; and purchase of HIV testing reagents, test kits and laboratory equipment for HIV testing and services. Equipment may be purchased if deemed necessary to accomplish program objectives; however, prior approval by CDC officials must be requested in writing. All requests for funds contained in the budget shall be stated in U.S. dollars. Once an award is made, CDC will not compensate foreign grantees for currency exchange fluctuations through the issuance of supplemental awards. The costs that are generally allowable in grants to domestic organizations are allowable to foreign institutions and international organizations, with the following exception: With the exception of the American University, Beirut, and the World Health Organization (WHO), Indirect Costs will not be paid (either directly or through sub-award) to organizations located outside the territorial limits of the United States or to international organizations regardless of their location. The applicant may contract with other organizations under this program; however the applicant must perform a substantial portion of the activities (including program management and operations, and delivery of prevention services for which funds are required). You must obtain an annual audit of these CDC funds (program-specific audit) by a U.S. - based audit firm with international branches and current licensure/authority in-country, and in accordance with International Accounting Standards or equivalent standard(s) approved in writing by CDC. A fiscal Recipient Capability Assessment may be required, prior to or post award, in order to review the applicant's business management and fiscal capabilities regarding the handling of U.S. Federal funds.
What are the requirements after being awarded this opportunity?
No program reports are required. No cash reports are required. As specified in the Founding Opportunity Announcement. No expenditure reports are required. As specified in the Founding Opportunity Announcement.
In accordance with the provisions of 2 CFR 200, Subpart F - Audit Requirements, non-Federal entities that expend financial assistance of $750,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Non-Federal entities that expend less than $750,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in 2 CFR 200.503. Foreign recipients are subject to audit requirements specified in 45 CFR 74.26(d). A non-Federal audit is required, if during the recipients fiscal year, the recipient expended a total of $300,000.00 or more under one or more HHS awards (as a direct recipient and/or as a subrecipient) . The recipient either may have (1) A financial related audit (as defined in the Government Auditing Standards, GPO stock #020-000-00-265-4) of a particular award in accordance with Government Auditing Standards, in those case where the recipient receives awards under only one HHS program; or, if awards are received under multiple HHS programs, a financial related audit of all HHS awards in accordance with Government Auditing Standards; or (2) An audit that meets the requirements contained in OMB Circular A-133. Please forward a copy of the completed audit to the following address: Procurement and Grants Office, Centers for Disease Control and Prevention, Attn: Grants Management Officer, 2920 Brandywine Road, MS-K75, Atlanta, GA 30341. If your audit was completed in accordance with number two (2) above, in addition to the address listed above, you are required to send a copy of the audit report to: Department of Health & Human Services, National External Audit Review Center Lucas Place, Room 514, 323 West 8th Street, Kansas City, MO 64105.
Financial records, including documents to support entries on accounting records and to substantiate charges to each grant, must be kept readily available for review by personnel authorized to examine PHS grant accounts. Records must be maintained for three years after the end of a budget period. If questions still remain, such as those raised as a result of audit, related records should be retained until the matter is completely resolved.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formulas are not applicable to this program.
Matching requirements are not applicable to this program.
MOE requirements are not applicable to this program.
Length and Time Phasing of Assistance
From one to five years. Throughout the project period, CDC's commitment to continuation of awards will be conditioned on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the Federal Government. Method of awarding/releasing assistance: lump sum.
Who do I contact about this opportunity?
Regional or Local Office
See Regional Agency Offices. Jamie Legier, Branch Chief, International Branch, (770)488-2613, 2920 Brandywine Road, Atlanta, GA 30341.
Headquarters Office
Kay Lawton 1600 Clifton Road, NE, Mailstop E-84, Atlanta, Georgia 30333 Email: Phone: (404) 498-1613
Website Address
Financial Information
Account Identification
(Cooperative Agreements) FY 14 $1,382,732,145; FY 15 est $1,368,481,580; and FY 16 est $1,368,481,580
Range and Average of Financial Assistance
$25,000 to $134,000,000. Average $2,200,000.
Regulations, Guidelines and Literature
45 CFR Part 74 and Part 92 For more information on the Code of Federal Regulations, see the National Archives and Records Administration at the following Internet address:
Examples of Funded Projects
Not Applicable.


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