Centers for Research and Demonstration for Health Promotion and Disease Prevention


The funded Prevention Research Centers aims are to: 1. Establish, maintain, and operate multi-disciplinary academic-based centers that conduct high-quality applied health promotion and disease prevention research; 2. Improve public health practice through applied prevention research; 3. Apply the knowledge and expertise of academic health centers to address practical public health problems; 4. Design, implement, evaluate, and disseminate cost-effective methods and strategies for health promotion and disease prevention at the tribal, territorial, state, or local level; 5. Shorten the time lag between the development of new and proven effective disease prevention and health promotion strategies and interventions and their widespread application; and 6. Involve health departments and other community partners in the development, implementation, evaluation, and dissemination of one applied public health prevention research project.

General information about this opportunity
Last Known Status
Program Number
Federal Agency/Office
Centers For Disease Control and Prevention, Department of Health and Human Services
Type(s) of Assistance Offered
B - Project Grants
Program Accomplishments
Not applicable.
Public Health Service Act, Title 42, Part 330u-5, Section 1706, Public Law 98-551
Section 317K of the Public Health Service Act, [42 U.S.C. 247b-12], as amended
Who is eligible to apply/benefit from this assistance?
Applicant Eligibility
Eligible applicants are accredited schools of medicine, schools of osteopathy, and schools of public health as defined in Section 701 (4) of Public Health Service Act.
Beneficiary Eligibility
Academic health centers, scientist/researchers, operational public health programs, targeted high risk groups, selected demonstration areas, and the general public.
Costs will be determined in accordance with HHS Regulations, 45 CFR 75.
What is the process for applying and being award this assistance?
Pre-Application Procedure
Preapplication coordination is not applicable.
Application Procedure
This program is excluded from coverage under 2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards.
Award Procedure
Approved grants are funded based on priority score ranking from a scientific review, as well as availability of funds, secondary review and such other significant factors deemed necessary and appropriate by the agency. After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, and special conditions, if any.
Contact the headquarters or regional location, as appropriate for application deadlines
Approval/Disapproval Decision Time
More than 180 days.
Not applicable.
Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.
How are proposals selected?
Prevention Research Center applications are reviewed on the basis of scientific/technical merit, with attention given to such matters as: (1) The degree to which the applicant satisfies the essential requirements and possesses other desired characteristics, such as depth, breadth, and scientific merit of the overall application relative to the types of research and demonstration projects proposed; (2) clarity of purpose and overall qualifications, adequacy and appropriateness of personnel to accomplish proposed prevention research projects and demonstration projects, and the nation's health priorities and needs; (3) ability to generalize, translate and disseminate to State or local health departments, boards of education and other appropriate national regional, and local public health agencies and organizations; (4) reasonableness of the proposed budget in relation to the work proposed.
How may assistance be used?
Funds are available for costs directly attributed to the performance of research and demonstration projects pertaining to health promotion and disease prevention plus certain indirect costs of the grantee in accordance with established policies of the Public Health Service. Grantees may not award subgrants but may enter into consortia agreements or contracts as necessary to achieve the aims of the program.
What are the requirements after being awarded this opportunity?
Performance Reports: Annual Federal Financial Reports (FFR) and performance/progress reports are required. Final FFRs and performance reports are required. Other reporting may be required and will be outlined in the NOFO or the Notice of Award.
In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal officials.
In accordance with 2 CFR ?200, as codified in 45 CFR ?75, there is a 3-year record retention requirement; records shall be retained beyond the 3-year period if final audit has not been done or findings resolved. Property records must be retained in accordance with HHS Grants Policy Statement requirements.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formula is not applicable to this assistance listing.

Matching requirements are not applicable to this assistance listing.

MOE requirements are not applicable to this assistance listing.
Length and Time Phasing of Assistance
Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient. Notice of Award
Who do I contact about this opportunity?
Regional or Local Office
None/Not specified.
Headquarters Office
Raman, Jayalakshmi (Jaya)
4770 Buford Highway
Chamblee, GA 30341 USA
Phone: 770.488.6511
Website Address
Financial Information
Account Identification
(Cooperative Agreements) FY 22$33,362,464.00; FY 23 est $30,549,444.00; FY 24 est $35,000,000.00; FY 21$43,992,554.00; FY 20$19,500,000.00; FY 19$18,735,550.00; FY 18$19,084,000.00; FY 16$19,084,000.00; FY 17 est $19,083,950.00; -
Range and Average of Financial Assistance
Range: $750,000 - $2,275,000 Average: $1,174,979
Regulations, Guidelines and Literature
Not applicable.
Examples of Funded Projects
Not applicable.


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