21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies
To provide support for initiatives funded under the 21st Century Cures Act to support the BRAIN Initiative?s aim of revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a revolutionary new dynamic picture of the brain that, for the first time, shows how individual cells and complex neural circuits interact in both time and space. Long desired by researchers seeking new ways to treat, cure, and even prevent brain disorders, this picture will fill major gaps in our current knowledge and
General information about this opportunity
Last Known Status
National Institutes of Health, Department of Health and Human Services
Type(s) of Assistance Offered
B - Project Grants
Fiscal Year 2016
N/AFiscal Year 2017
$10,000,000Fiscal Year 2018
Small Business Research and Development Enhancement Act of 1992, Public Law 102-564
Act: The 21st Century Cures Act; Appropriation 75X5628
Who is eligible to apply/benefit from this assistance?
The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that applies and receives a grant for support of research by a named principal investigator. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council.
Any nonprofit or for-profit organization, company, or institution engaged in biomedical research.
Applications must be submitted in compliance with instructions provided with each initiative.
What is the process for applying and being award this assistance?
Preapplication coordination is not applicable.
This program is excluded from coverage under 2 CFR 200, Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards.
Grants and cooperative agreements are funded based on scientific merit, program relevance, and program balance and are made annually. The initial grant award provides funds for the first budget period (usually 12 months) and letter Notice of Award indicates support recommended for the remainder of the project period, allocation of Federal funds by budget categories and special conditions, if any.
Approval/Disapproval Decision Time
Regular Grants: Approximately 10 months
A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/notice-files/not97-232.html .
Applications submitted for renewal are reviewed and selected for funding on a competitive basis.
How are proposals selected?
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
How may assistance be used?
Grants and cooperative agreements may be made to eligible institutions for the support of the BRAIN Initiative. The grants and cooperative agreements may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and Facilities and Administrative Costs (formerly known as indirect costs).
What are the requirements after being awarded this opportunity?
Expenditures and other financial records, and also administrative records, must be retained for 3 years from the day on which the grantee submits the last expenditure report for the grant period.
Other Assistance Considerations
Formula and Matching Requirements
Statutory formula is not applicable to this assistance listing.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Length and Time Phasing of Assistance
Grants and Cooperative Agreements: Average 3 to 5 years, and a maximum of 5 years. Renewals may be awarded for additional periods of up to 5 years based on competitive peer review. Funding is provided through Monthly Demand Payment System or an Electronic Transfer System. Method of awarding/releasing assistance: by letter of credit.
Who do I contact about this opportunity?
Regional or Local Office
National Institutes of Health
31 Center Drive, Room 8A52
Bethesda, MD 20892 US
(Project Grants (Cooperative Agreements)) FY 18$86,000,000.00; FY 19 est $115,000,000.00; FY 20 est $140,000,000.00; FY 17$10,000,000.00; FY 16$0.00; -
Range and Average of Financial Assistance
Regulations, Guidelines and Literature
45 CFR 75, NIH Grants Policy Statement, SF 424